Lucas Ferrari de Andrade recently showed how MICA antibodies block proteolytic shedding and enable activation of NK cells through the NKG2D and CD16 receptors. This results in potent NK cell-mediated tumor immunity. Read all about it here.
Kai, along with UCSF immunoloist Lewis Lanier, recently discussed the difficulty, direction, and hope of immunotherapy on a recent episode of Science Friday. You can listen here.